Prevalence of Malnutrition among Pediatric Celiac Disease
DOI:
https://doi.org/10.47941/ijhs.1173Keywords:
children, Celiac disease, malnutrition, nutrition status, prevalence of undernutritionAbstract
Purpose: Celiac Disease (CD) is an autoimmune systemic disorder triggered by gluten in genetically susceptible individuals, which can lead to chronic malabsorption. Considering the changes in the manifestations of CD.The present study was designed to determine the nutritional status and prevalence of malnutrition of celiac disease in children and to investigate the nutritional markers, anthropometric parameters such as body mass index (BMI), meal patterns ,and routine laboratory in celiac disease children
Methodology: This cross-sectional study aimed to evaluate the children with CD who had referred to Pediatric gastroenterology Clinic between 2021 and 2022. Totally, 40 children were eligible, and their weight, height, and Body Mass Index (BMI) were extracted by interview. The anthropometric indices were presented based on the criteria of the Center for Disease Control and Prevention (CDC) and World Health Organization (WHO). Biochemical tests were obtained during the study period from medical files of the studied patients. Data were analyzed using descriptive statistics. The Chi-Square test was applied to examine the study data.
Findings: Data shows that 52% of CD children were well-nourished while the remaining 45%, 3%had moderate -to-severe malnutrition. Regarding the height for age and weight for age 20% of the participants had short stature, 80% were normal stature, in addition ,40% of the patients had sever wasting for age and 43% had normal weight for age. Based on the CDC's criteria 20%,65%, 10%, and 20% low BMI, normal BMI, overweight, and obese for age respectively. In addition, results show that most of CD children had normal hemoglobin level with low level of vitamin D. Regarding to meals pattern of CD children result revealed that the most kind of food daily intake was milk and white bread while there was not daily consumed of ice cream and whole wheat bread.
Conclusion: To sum up, the results clearly indicated that growth failure and low height, weight, and BMI were less prevalent among the studied group of children with CD. Early diagnosis of celiac disease is very important to prevent long-term complications, early initiation of nutritional intervention and treatment is important. Currently, the only effective treatment is a lifelong gluten-free diet.
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Ludvigsson, J. F., Leffler, D. A., Bai, J. C., Biagi, F., Fasano, A., Green, P. H., ... & Ciacci, C. (2013). The Oslo definitions for coeliac disease and related terms. Gut, 62(1), 43-52.
Greco, L., Timpone, L., Abkari, A., Abu-Zekry, M., Attard, T., Bouguerrà , F., ... & Terzic, S. (2011). Burden of celiac disease in the Mediterranean area. World journal of gastroenterology: WJG, 17(45), 4971..
Dehghani, S. M., Haghighat, M., Mobayen, A., Rezaianzadeh, A., & Geramizadeh, B. (2013). Prevalence of celiac disease in healthy Iranian school children. Annals of Saudi medicine, 33(2), 159-161.
Sahin, Y., Cakir, M. D., Isakoca, M., & Sahin, D. A. (2020). Prevalence of celiac disease in children with type 1 diabetes mellitus in the South of turkey. Iranian Journal of Pediatrics, 30(1). Weiss B, Pinhas-Hamiel O. Celiac Disease and Diabetes: When to Test and Treat. J Pediatr Gastroenterol Nutr. 2017;64:175-179. [PubMed] [Google Scholar]
Liu, E., Wolter-Warmerdam, K., Marmolejo, J., Daniels, D., Prince, G., & Hickey, F. (2020). Routine screening for celiac disease in children with down syndrome improves case finding. Journal of pediatric gastroenterology and nutrition, 71(2), 252-256.
Wierdsma, N. J., van Bokhorst-de van der Schueren, M. A., Berkenpas, M., Mulder, C. J., & van Bodegraven, A. A. (2013). Vitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients. Nutrients, 5(10), 3975-3992.
van der Pals, M., Mylus, A., Norström, F., Hammarroth, S., Högberg, L., Rosn, A., ... & Carlsson, A. (2014). Body mass index is not a reliable tool in predicting celiac disease in children. BMC pediatrics, 14(1), 1-6.
Brambilla, P., Picca, M., Dilillo, D., Meneghin, F., Cravidi, C., Tischer, M. C., ... & Zuccotti, G. V. (2013). Changes of body mass index in celiac children on a gluten-free diet. Nutrition, Metabolism and Cardiovascular Diseases, 23(3), 177-182.
Clinical Growth Charts. Available from: https://www.cdc.gov/growthcharts/clinical_charts.htm. Accessed 8 Nov 2020
Cornean, R. E., Gheban, D., Simionescu, B., & Margescu, M. (2018). Celiac disease among adolescents. Poor growth and delayed puberty. Int J Celiac Dis, 2, 52-7.
Tümer, L., Hasanoglu, A., & Aybay, C. (2001). Endomysium antibodies in the diagnosis of celiac disease in short"statured children with no gastrointestinal symptoms. Pediatrics International, 43(1), 71-73.
Catassi, C., & Fasano, A. (2004). Celiac disease as a cause of growth retardation in childhood. Current opinion in pediatrics, 16(4), 445-449.
Giovenale, D., Meazza, C., Cardinale, G. M., Sposito, M., Mastrangelo, C., Messini, B., ... & Bozzola, M. (2006). The prevalence of growth hormone deficiency and celiac disease in short children. Clinical medicine & research, 4(3), 180-183.
Assiri, A. M. A. (2010). Isolated short stature as a presentation of celiac disease in Saudi children. Pediatric reports, 2(1), e4.
Masood, J., Rehman, H., Anjum, Z. M., Iqbal, I., Zafar, S., & Ayesha, H. (2020). Prevalence of celiac disease in idiopathic short stature children presenting in OPD of children hospital, Faisalabad. Annals of Punjab Medical College, 14(1), 9-12.
Farooq, A., Sheikh, T. K., Bashir, H., & Haroon, S. (2020). Celiac Disease in children and the impact of late diagnosis. Methodology, 12(3), 136-40.
Bardella, M. T., Fredella, C., Prampolini, L., Molteni, N., Giunta, A. M., & Bianchi, P. A. (2000). Body composition and dietary intakes in adult celiac disease patients consuming a strict gluten-free diet. The American journal of clinical nutrition, 72(4), 937-939.
Barera, G., Mora, S., Brambilla, P., Ricotti, A., Menni, L., Beccio, S., & Bianchi, C. (2000). Body composition in children with celiac disease and the effects of a gluten-free diet: a prospective case-control study. The American journal of clinical nutrition, 72(1), 71-75.
Dehbozorgi, M., Honar, N., Ekramzadeh, M., & Saki, F. (2020). Clinical manifestations and associated disorders in children with celiac disease in southern Iran. BMC pediatrics, 20(1), 1-7.
Calcaterra, V., Regalbuto, C., Manuelli, M., Klersy, C., Pelizzo, G., Albertini, R., ... & Cena, H. (2020). Screening for celiac disease among children with overweight and obesity: toward exploring celiac iceberg. Journal of Pediatric Endocrinology and Metabolism, 33(8), 995-1002.
Nenna, R., Mosca, A., Mennini, M., Papa, R. E., Petrarca, L., Mercurio, R., ... & Vania, A. (2015). Coeliac disease screening among a large cohort of overweight/obese children. Journal of pediatric gastroenterology and nutrition, 60(3), 405-407.
Al-Hussaini, A., Troncone, R., Khormi, M., AlTuraiki, M., Alkhamis, W., Alrajhi, M., ... & Elchentoufi, A. (2017). Mass screening for celiac disease among school-aged children: Toward exploring celiac iceberg in Saudi Arabia. Journal of pediatric gastroenterology and nutrition, 65(6), 646-651.
Singh, I., Agnihotri, A., Sharma, A., Verma, A. K., Das, P., Thakur, B., ... & Makharia, G. K. (2016). Patients with celiac disease may have normal weight or may even be overweight. Indian Journal of Gastroenterology, 35(1), 20-24.
Valletta, E., Fornaro, M., Cipolli, M., Conte, S., Bissolo, F., & Danchielli, C. (2010). Celiac disease and obesity: need for nutritional follow-up after diagnosis. European journal of clinical nutrition, 64(11), 1371-1372.
Diamanti, A., Capriati, T., Basso, M. S., Panetta, F., Di Ciommo Laurora, V. M., Bellucci, F., ... & Francavilla, R. (2014). Celiac disease and overweight in children: an update. Nutrients, 6(1), 207-220.
Penagini, F., Dilillo, D., Meneghin, F., Mameli, C., Fabiano, V., & Zuccotti, G. V. (2013). Gluten-free diet in children: an approach to a nutritionally adequate and balanced diet. Nutrients, 5(11), 4553-4565.
Sánchez, E., Laparra, J. M., & Sanz, Y. (2012). Discerning the role of Bacteroides fragilis in celiac disease pathogenesis. Applied and environmental microbiology, 78(18), 6507-6515.
Bardella, M. T., Fredella, C., Prampolini, L., Molteni, N., Giunta, A. M., & Bianchi, P. A. (2000). Body composition and dietary intakes in adult celiac disease patients consuming a strict gluten-free diet. The American journal of clinical nutrition, 72(4), 937-939.
Mariani, P., Viti, M. G., Montouri, M., La Vecchia, A., Cipolletta, E., Calvani, L., & Bonamico, M. (1998). The gluten-free diet: a nutritional risk factor for adolescents with celiac disease?. Journal of pediatric gastroenterology and nutrition, 27(5), 519-523.
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